High-activity Pepsin for controlled protein breakdown under strongly acidic conditions. Ideal for protein digestion support, milk-clotting process development, and research workflows requiring reproducible acid proteolysis. Works best within recommended pH and temperature ranges. Activity 1:10,000 – 1:15,000 NF (pepsin activity ratio). Optimal pH 1.5–3.5 and 37°C–42°C. White to pale yellow powder. MOQ 1 kg. Ships worldwide.
ISO 9001 certified
Pepsin (EC 3.4.23.1)
1:10,000 – 1:15,000 NF (pepsin activity ratio)
1.5 – 3.5
37°C – 42°C
White to pale yellow powder
Porcine gastric mucosa
24 months (sealed, refrigerated)
1 kg / 5 kg / 25 kg
1 kg
USP/NF, EP, ISO 9001, HALAL
Pepsin hydrolyzes proteins into peptides and smaller fragments under acidic conditions. Designed for consistent performance across supplement manufacturing, food processing, and advanced analytical and biomedical workflows.
Milk-clotting enzyme for cheese production—used as a partial rennet substitute in specific cheese varieties where acid proteolysis supports curd development.
Active ingredient in digestive enzyme supplements to support protein digestion—standardized NF/USP grades for reliable formulation.
Pepsin digestion for HDX-MS sample preparation in structural biology research, enabling controlled proteolysis for peptide mapping.
Generates F(ab')2 fragments from IgG antibodies for diagnostic and therapeutic workflows in immunology.
Supports extraction of acid-soluble collagen (pepsin-solubilized collagen) from animal tissues for medical and cosmetic use.
USP/EP certified pepsin for pharmaceutical manufacturing—API production and quality control applications.
Pepsin is used for 🧀 cheese rennet alternative applications, 💊 digestive supplement protein digestion support, 🧬 HDX-MS sample preparation, 🔬 antibody F(ab')2 generation, 🐄 pepsin-solubilized collagen workflows, and 🧪 pharmaceutical manufacturing where acidic proteolysis is required.
Use Pepsin in the pH 1.5–3.5 range and operate at 37°C–42°C for best activity and process consistency.
The NF activity ratio reflects measured pepsin potency. Higher ratios generally indicate stronger proteolytic activity, but final dosing should be confirmed in your specific formulation or digestion protocol.
Pepsin has a 24-month shelf life when sealed and refrigerated. Minimize moisture exposure and follow the storage guidance provided with your COA/TDS.
Packaging is available in 1 kg, 5 kg, and 25 kg. MOQ starts at 1 kg, supporting both pilot studies and commercial scale supply.
Certifications & Standards
Tell us your application and required grade. We’ll recommend the right Pepsin activity level and send a free sample, COA, and competitive pricing within 24 hours.
Years experience
Countries shipped